GHK-CU

What is GHK-CU?

The human copper-binding peptide GHK-Cu (glycyl-l-histidyl-l-lysine) is a small, naturally occurring tri-peptide present in human plasma that can also be released from tissues in case of an injury. Since its discovery in 1973, GHK-Cu has established itself as a powerful protective and regenerative ingredient currently widely used in skin and hair products.

Benefits:

  • Promotes the release of proteins that repair and build tissue.
  • Stimulates collagen production.
  • Possesses antioxidant, anti-inflammatory, and regenerative properties
  • Improves circulation
  • Supports stem cell functions
  • Promotes nerve outgrown and synthesis of neurotrophic factors. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073405/

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NAD+

What is NAD+?

NAD+ stands for nicotinamide adenine dinucleotide.

The classic role of NAD + is a co-enzyme that catalyzes cellular redox reactions, becoming reduced to NADH, in many fundamental metabolic processes, such as glycolysis, fatty acid beta-oxidation, or the tricarboxylic acid cycle, which is the main source of energy for ALL cells.

 NAD+ not only helps convert food to energy but also plays a crucial role in maintaining DNA integrity in the mitochondria and ensures proper cell function to protect our bodies from aging and disease.

Aging is marked by a systemic decrease in NAD + across multiple tissues. The dysfunction of NAD + biosynthesis plays a critical role in the pathophysiology of multiple diseases, including age-associated metabolic disorders, neurodegenerative diseases, and mental disorders. 

Benefits of NAD+:

  • Increased mental clarity
  • Better memory
  • High concentration
  • Improved moods
  • Better problem-solving skills
  • It activates your brain’s neuron function to help regenerate cells and protect the brain against cellular damage. This increases mental cognition and improves mental clarity, concentration, and memory.
  • It improves your metabolism, making you feel more energetic and youthful, resulting in better physical performance and greater endurance.
  • It can help improve conditions such as depression, anxiety, addictive tendencies, and mood disorders.
  • It replenishes your levels of NAD that infections, metabolic stress, alcohol abuse, or other factors have depleted.
  • It helps in the management of the effects of aging and age-related conditions.

Skin renewal requires a significant amount of energy at the cellular level to help in the desquamation process, where new skin cells are created, broken down, and replaced on the outermost layer of the skin. Results in clinical studies have shown that injectable and/or topical application of NAD+ can improve the appearance of aging skin. It has been shown to increase skin smoothness due to improved cellular turnover. It also improves fine lines and wrinkles, hyperpigmentation, skin yellowing, pore size, erythema, and sebum excretion and is well tolerated by the skin. Overall, it can strengthen the skin barrier while improving skin functions and increasing elasticity and hydration.

NAD therapy can help improve various skin concerns, such as:

  • Sagging skin
  • Wrinkles and fine lines
  • Hyperpigmentation
  • Dull skin
  • Rough skin texture
  • Dark spots
  • Loss of skin volume

Injections of NAD+ seem to be secure and well-tolerated. The injection of NAD+ may cause adverse reactions and side effects, such as headache, shortness of breath, and constipation, which usually last minutes after the injection. Therefore, we start at a low dose and titrate up.

 Also, in certain situations, NAD+ can increase plasma bilirubin and decrease levels of gamma-glutamyl transferase, lactate dehydrogenase, and aspartate aminotransferase, which is why we check your liver and kidney function periodically.

How quickly can I see the benefits of NAD+?

Almost immediately. Patients report mental clarity and energy within hours of taking their first dose. 

How does NAD+ differ from HRT therapies?

Supplementing NAD+ does not replace the natural occurring levels of NAD in our body. It simply helps your cells work better. NAD is a “helper” coenzyme. It works by transporting electrons from one place to another inside a cell. So, you can think of each NAD coenzyme as a tiny shuttle bus responsible for taking electrons to work inside the mitochondria (the part of the cell responsible for metabolizing nutrients).

HRT therapies are used when the body’s hormone levels are low or not optimal.  

Both therapies can have the same benefits and can be used simultaneously.

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Biotin B7

What is Biotin B7?

Biotin is a water-soluble B vitamin involved in essential enzyme activity and plays a major role in maintaining an increased metabolic rate. When the biotin depletion continues for extended periods, and the levels of biotin get too low, patients can notice symptoms like hair loss, damaged hair, and fragile nails.

Benefits:

  • Strengthens hair
  • Promotes hair growth
  • Prevents hair loss and dryness
  • Supports hair thickness
  • Reduces split ends
  • Restores hair elasticity
  • Strengthens the nails
  • Improves blood glucose
  • Stabilizes blood sugar levels
  • Accelerates metabolism and digestion
  • Helps with weight loss

Recommended dosing schedule: *can differ with each patient

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MOTS-C 10mg

Mots-c is a peptide consisting of 16 amino acids transcribed specifically from the mitochondrial genome.

Detailed studies and thorough analysis confirm that mots-c helps regulate several metabolic pathways in energy production. The peptide assists in weight regulation, exercise, longevity, and glucose metabolism. Due to its widespread systemic effects, mots-c is a therapeutic peptide that can be used for recreational purposes.

Benefits:

  • Promotes Weight Loss
  •  Increases the use of energy reservoirs such as glucose and fatty acids. This, in turn, reduces fatty tissue for energy production and expenditure.
  • Researchers report a significant decrease in obesity in rats fed a high-fat diet and supplemented with Mots-c.
  • Improves Exercise Regimens. Due to its ability to enhance insulin sensitivity and energy production, one can use Mots-c to optimize exercise regimens. The peptide can increase endurance and energy levels for cardio exercises.
  • Improve physical performance. It has been shown to increase running time, increase endurance, and increase maximal speed, in part by modulating skeletal muscle function and improving “metabolic flexibility.”
  • Optimizes Mitochondrial Health. Some studies also suggest a rather protective action of Mots-c in mitochondrial health. The peptide can help protect mitochondrial DNA against free radicals and oxidative stresses. It also increases your natural production of NAD and mitochondrial efficiency.
  • Improves Cardiovascular Health and Function. Studies have shown that supplementing with MOTS-c has improved endothelial and epicardial blood vasculature, leading to advanced heart functions.
  • Anti-Aging Effects. Mots-c reduces excessive inflammation and osteoporosis of bones, improves insulin resistance and glucose metabolism, uptakes the function of NAD production, and slows down the aging process.

There are no known side effects of MOTs-C injections. There may be injection site irritation.

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BPC-157 10mg

Multiple studies have found BPC to significantly stimulate angiogenesis – the production of new vessels by modulating a growth factor known as VEGF. What this does is encourage the growth of capillaries into new areas, and this, in turn, enables blood and, henceforth, nutrients to be delivered to that area – a process that drives healing.

The growth hormone-stimulating properties of BPC-157 have also been suggested to stimulate cell growth. When applied to areas such as the joint tendons, this could lead to not only tendon healing but total regeneration over time and also a reduction in joint pain and inflammation.

This is a great summary: http://www.world-of-peptides.com/a-summary-of-studies-bpc-157/

Study: https://pubmed.ncbi.nlm.nih.gov/21030672/

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DUO-BLEND 156 IPAMORELIN/CJC 1295 15MG/6MG

Ipamorelin is a Growth Hormone (GH) Secretagogue comprised of 5 amino acids.  Its presence plays a key role in overall growth, including bone and muscular and skeletal tissue, stimulates insulin release from the pancreas, improves sugar metabolism, and improves hair, skin, and nails. 

When Ipamorelin is injected, a selective pulse travels to the brain. The pulse stimulates the hypothalamus and the anterior pituitary glands. Once stimulated, the glands will release growth hormones. The activated cells go directly to muscles to support development (hence, growth hormones). 

CJC-1295 increases Growth Hormone but it does so by stimulating Growth Hormone Receptor Sites. It is also highly selective and its positive benefits include bone health, muscle growth and repair improvement in insulin resistance, fat loss, hair, skin nails, joint pain, sleep.

Combining these two Peptides will enhance GH production and receptor site sensitivity.

Ipamorelin will increase baseline levels of GH, and CJC will increase the peaks and troughs.

Natural production of GH is not shut down with these peptides like synthetic GH.

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Tesamorelin Acetate 8mg/mL

Tesamorelin is a growth hormone-releasing analog that can increase IGF-1 levels in men and women by an average of 181 micrograms/liter. This growth hormone can bind and stimulate the GHRH receptors that have a similar potency to GHRH. This growth hormone also hosts many benefits, which include Nootropic effects, Reducing triglycerides, decreased carotid intima-media thickness (cIMT), visceral adipose tissue (VAT), and c-reactive protein (CRP.) This growth hormone has not been linked to significantly affect other pituitary hormones and other respective mechanisms of the body. Tesamorelin can also improve cognitive function for people with old age and patients with an increased risk of Alzheimer’s disease due to mild cognitive impairment. 

More Education: Over time, the injections will:

  • Increase cell synthesis
  • Elevate insulin secretion from the pancreas
  • Elevate ghrelin levels in the stomach.

These processes promote fat loss, redistribution of nutrients, and building healthy muscle mass. 

There is no shutdown of natural HGH production as happens with synthetic HGH protocols.

This is due to the steady pulse the peptide sends to the pituitary gland. Instead of remaining in an elevated state, hormone levels move more naturally. Keeping your body happy.

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EPITALON 10MG

Epitalon is considered the “fountain of youth” peptide. It is a tetra-peptide, which means that it is composed of four amino acid chains. The peptide is used to regulate the cell cycle during telomerase activity. Telomerase, or telomere terminal transferase, is an enzyme made of protein and RNA subunits that elongate chromosomes. When telomerase activity is absent (when we age), our cells age. Our telomeres get shorter and begin to die off. If telomerase is activated in our cells, our telomeres lengthen, the cell continues to grow and divide, delaying the aging process.

Benefits:

  • Increase human lifespan
  • Delay/Prevent age-related diseases
  • Boost energy levels
  • Promote deeper sleep
  • Improve skin health and appearance
  • Heal deteriorated/injured muscle cells

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